LYN-1604 System

LYN-1604 SystemLYN 1604 is a potential ULK1 agonist with IC50 of 1. 66 ? M against MDA MB 231 cells and it binds to wild type ULK1 with a binding affinity in the nanomole range (Kd=291. 4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants.

inhibits UDP-glucuronosyltransferase (UGT) isoforms UGT1A6 and UGT2B7 with immunosuppressive effects

Flt-1/3 and PDGFR

Corning The capacity tolerance on this Class A 50mL PYREX® buret is established by ASTM E-287 and is calibrated in accordance with ASTM E-542

>10-fold selectivity against MNK2

available to users

CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM

TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays

used to treat non-allergic and allergic rhinitis

Phenazine methosulfate is widely used as an intermediate electron carrier for coupling the production of NADH or NADPH to the reduction of tetrazolium salts to coloured formazans

84/Case - COP

and selective Eg5 mitotic motor protein inhibitor

abrogates Stat3 phosphorylation and nuclear translocation