BMS-935177 Porosity

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Description

BMS-935177 PorosityBMS 935177 is a potent, reversible Bruton's Tyrosine Kinase (BTK) inhibitor with an IC50 value of 2. 8 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5 and 67 fold selective.

Corning This 47 mm fritted glass support base is designed for assembly with either the 300 mL graduated glass funnel

Disopyramide possesses significant negative inotropic

Corning These 45x450mm PYREX® Flash columns are ideal for use when quick separations in absorption chromatography applications are desired

used against diarrhea resulting from gastroenteritis or inflammatory bowel disease

-adrenergic receptor agonist with EC50 of 0

Benznidazole is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis

-secretase inhibitor with IC50 of 0

selective inhibitor of the serine protease dipeptidyl peptidase IV (DPP-4) with IC50 values of 2

without significant inhibition on 26 other kinases tested

3 nM for hMDM2 in TR-FRET assay

acts as a coenzyme in all transamination reactions

Fenspiride is a bronchodilator with anti-inflammatory properties

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