LFM-A13 Class A

LFM-A13 Class ALFM A13 is a specific Bruton's tyrosine kinase (BTK) inhibitor with IC50 of 2. 5 ? M, >100 fold selectivity over other protein kinases including JAK1, JAK2, HCK, EGFR,and IRK.

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and CSF-1R

inhibits UDP-glucuronosyltransferase (UGT) isoforms UGT1A6 and UGT2B7 with immunosuppressive effects

RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay

Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59

Betamipron is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity

urinary tract

insects and acari

Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine that occurs during protein hydrolysis during putrefaction of animal tissue

the cytosolic isozyme (Ki=10

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1-adrenergic receptor agonist